Repellent active ingredients encapsulated in polymeric nanoparticles: potential alternative formulations to control arboviruses.

ABSTRACT: Dengue, yellow fever, Chinkungunya, Zika virus, and West Nile fever have infected millions and killed a considerable number of humans since their emergence. These arboviruses are transmitted by mosquito bites and topical chemical repellents are the most commonly used method to protect against vector arthropod species. This study aimed to develop a new generation of repellent formulations to promote improved arboviruses transmission control. A repellent system based on polycaprolactone (PCL)-polymeric nanoparticles was developed for the dual encapsulation of IR3535 and geraniol and further incorporation into a thermosensitive hydrogel. The physicochemical and morphological parameters of the prepared formulations were evaluated by dynamic light scattering (DLS), nano tracking analysis (NTA),

SUBMITTER: Abrantes DC 

PROVIDER: S-EPMC9741802 | biostudies-literature | 2022 Dec

REPOSITORIES: biostudies-literature