Black phosphorous-based biomaterials for bone defect regeneration: a systematic review and meta-analysis.

ABSTRACT: Critical-sized bone defects are always difficult to treat, and they are associated with a significant burden of disease in clinical practice. In recent decades, due to the fast development of biomaterials and tissue engineering, many bioinspired materials have been developed to treat large bone defects. Due to the excellent osteoblastic ability of black phosphorous (BP), many BP-based biomaterials have been developed to treat bone defects. Therefore, there are abundant studies as well as a tremendous amount of research data. It is urgent to conduct evidence-based research to translate these research data and results into validated scientific evidence. Therefore, in our present study, a qualitative systematic review and a quantitative meta-analysis were performed. Eighteen studies were incl

SUBMITTER: Huang J 

PROVIDER: S-EPMC9741806 | biostudies-literature | 2022 Dec

REPOSITORIES: biostudies-literature