Effects of changes in inspired oxygen fraction on urinary oxygen tension measurements.

ABSTRACT:

Background

Continuous measurement of urinary PO₂ (PuO₂) is being applied to indirectly monitor renal medullary PO₂. However, when applied to critically ill patients with shock, its measurement may be affected by changes in FiO₂ and PaO₂ and potential associated O₂ diffusion between urine and ureteric or bladder tissue. We aimed to investigate PuO₂ measurements in septic shock patients with a fiberoptic luminescence optode inserted into the urinary catheter lumen in relation to episodes of FiO₂ change. We also evaluated medullary and urinary oxygen tension values in Merino ewes at two different FiO₂ levels.

Results

In 10 human patients, there were 32 FiO₂ decreases an

SUBMITTER: Osawa EA 

PROVIDER: S-EPMC9742069 | biostudies-literature | 2022 Dec

REPOSITORIES: biostudies-literature