Effect of Vitamin D Supplementation on Overactive Bladder and Urinary Incontinence Symptoms in Older Men: Ancillary Findings From a Randomized Trial.

ABSTRACT:

Purpose

Our goal was to evaluate vitamin D supplementation for preventing or treating overactive bladder and urinary incontinence in men.

Materials and methods

Ancillary study of men aged ≥55 years in VITAL (VITamin D and OmegA-3 TriaL). Randomized treatments included: vitamin D₃ (cholecalciferol), marine omega-3 fatty acids, or matching placebo. Structured urinary incontinence questions measured the prevalence of overactive bladder at year 5 and urinary incontinence at years 2 and 5, along with incidence and progression of urinary incontinence from years 2 to 5. Prespecified subgroup analyses examined men with low baseline serum 25-hydroxyvitamin D (<20 ng/mL).

Results

Among the 11,486 men who provided data at year 2 and 10,474 at year 5, mean age was 68 y

SUBMITTER: Markland AD 

PROVIDER: S-EPMC9742141 | biostudies-literature | 2023 Jan

REPOSITORIES: biostudies-literature