Sex-related differences in clinical characteristics of children with ASD without ID: Results from the ELENA cohort.

ABSTRACT:

Objective

The literature on sex related-clinical differences for children with autism spectrum disorder (ASD) is highly contradictory, whereas this topic has major clinical implications. We aimed to investigate sex-related clinical differences in children with ASD without intellectual disability (ID).

Materials and methods

We compared 319 boys and 65 girls with ASD without ID, aged from 2 to 12 years, recruited from a multiregional cohort on their clinical profiles based on the scores for the Vineland-II, the SRS-2, the ADOS calibrated severity score, sensory processing, aberrant behaviors, and comorbidity rates.

Results

Our results confirm a high sex ratio of 4.9 males/females. Many similarities were found in the clinical profiles. However, we found that girls had hi

SUBMITTER: Dellapiazza F 

PROVIDER: S-EPMC9742240 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature