Ontology highlight
ABSTRACT:
SUBMITTER: Wang C
PROVIDER: S-EPMC9742439 | biostudies-literature | 2022
REPOSITORIES: biostudies-literature
Wang Cheng C Mei Xianghuang X Wu Yanrong Y Yang Yuting Y Zeng Zhenguo Z
Frontiers in pharmacology 20221128
Acute lung injury (ALI) is a severe clinical disorder characterized by dysregulated inflammatory responses, leading to high rates of morbidity and mortality. Cinobufagin, a primary component isolated from cinobufotalin, exerts strong anticancer effects. However, there are few reports on its role in ALI, and it is unclear whether cinobufagin affects lipopolysaccharide (LPS)-induced ALI. Therefore, the present study aimed to investigate the effect of cinobufagin on LPS-induced ALI and to assess it ...[more]