Competition for recruitment in SARS-CoV-2 Trials in the United States: a longitudinal cohort analysis.

ABSTRACT:

Objective

Competition among trials for patient enrollment can impede recruitment. We hypothesized that this occurred early in the COVID-19 pandemic, when an unprecedented number of clinical trials were launched. We performed a simple and multivariable regression analysis evaluating the relationship between the proportion of SARS-CoV-2 investigational trial sites within each USA state with unsuccessful patient-participant recruitment and: (i) the proportion of cases required to reach state recruitment goals; (ii) state population based on data from the US Census; and, (iii) number of trial sites per state.

Results

Our study included 151 clinical trials. The proportion of trials with successful recruitment was 72.19% (109 of 151 trials). We did not find a significant relations

SUBMITTER: Hutchinson N 

PROVIDER: S-EPMC9742655 | biostudies-literature | 2022 Dec

REPOSITORIES: biostudies-literature