Association of COVID-19 mortality with serum selenium, zinc and copper: Six observational studies across Europe.

ABSTRACT:

Introduction

Certain trace elements are essential for life and affect immune system function, and their intake varies by region and population. Alterations in serum Se, Zn and Cu have been associated with COVID-19 mortality risk. We tested the hypothesis that a disease-specific decline occurs and correlates with mortality risk in different countries in Europe.

Methods

Serum samples from 551 COVID-19 patients (including 87 non-survivors) who had participated in observational studies in Europe (Belgium, France, Germany, Ireland, Italy, and Poland) were analyzed for trace elements by total reflection X-ray fluorescence. A subset (n=2069) of the European EPIC study served as reference. Analyses were performed blinded to clinical data in one analytical laboratory.

Results

SUBMITTER: Demircan K 

PROVIDER: S-EPMC9742896 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature