Stool energy density is positively correlated to intestinal transit time and related to microbial enterotypes.

ABSTRACT:

Background

It has been hypothesised that the gut microbiota causally affects obesity via its capacity to extract energy from the diet. Yet, evidence elucidating the role of particular human microbial community structures and determinants of microbiota-dependent energy harvest is lacking.

Results

Here, we investigated whether energy extraction from the diet in 85 overweight adults, estimated by dry stool energy density, was associated with intestinal transit time and variations in microbial community diversity and overall structure stratified as enterotypes. We hypothesised that a slower intestinal transit would allow for more energy extraction. However, opposite of what we expected, the stool energy density was positively associated with intestinal transit time. Stratificati

SUBMITTER: Boekhorst J 

PROVIDER: S-EPMC9743556 | biostudies-literature | 2022 Dec

REPOSITORIES: biostudies-literature