Transcriptome analysis provides insights into light condition effect on paclitaxel biosynthesis in yew saplings.

ABSTRACT:

Background

Taxus is a rare gymnosperm plant that is the sole producer of the anticancer drug paclitaxel. The growth and development of Taxus is affected by environmental factors such as light. However, little is known about how light conditions affect growth and metabolic processes, especially paclitaxel biosynthesis.

Results

In this study, we applied three different light conditions to Taxus chinensis young saplings and investigated the physiological response and gene expression. Our observations showed that exposure to high light led to oxidative stress, caused photoinhibition, and damaged the photosynthetic systems in T. chinensis. The paclitaxel content in T. chinensis leaves was significantly decreased after the light intensity increased. Transcriptomic analysis reveale

SUBMITTER: Li T 

PROVIDER: S-EPMC9743728 | biostudies-literature | 2022 Dec

REPOSITORIES: biostudies-literature