Detection of prostate cancer bone metastases with fast whole-body ^99mTc-HMDP SPECT/CT using a general-purpose CZT system.

ABSTRACT:

Background

We evaluated the effects of acquisition time, energy window width, and matrix size on the image quality, quantitation, and diagnostic performance of whole-body ^99mTc-HMDP SPECT/CT in the primary metastasis staging of prostate cancer.

Methods

Thirty prostate cancer patients underwent ^99mTc-HMDP SPECT/CT from the top of the head to the mid-thigh using a Discovery NM/CT 670 CZT system with list-mode acquisition, 50-min acquisition time, 15% energy window width, and 128 × 128 matrix size. The acquired list-mode data were resampled to produce data sets with shorter acquisition times of 41, 38, 32, 26, 20, and 16 min, narrower energy windows of 10, 8, 6, and 4%, and a larger matrix size of 256 × 256. Images were qualitatively evaluated by three exp

SUBMITTER: Arvola S 

PROVIDER: S-EPMC9743860 | biostudies-literature | 2022 Dec

REPOSITORIES: biostudies-literature