Time-dependent risk of COVID-19 death with overwhelmed health-care capacity in Japan, 2020-2022.

ABSTRACT:

Background

It has been descriptively argued that the case fatality risk (CFR) of coronavirus disease (COVID-19) is elevated when medical services are overwhelmed. The relationship between CFR and pressure on health-care services should thus be epidemiologically explored to account for potential epidemiological biases. The purpose of the present study was to estimate the age-dependent CFR in Tokyo and Osaka over time, investigating the impact of caseload demand on the risk of death.

Methods

We estimated the time-dependent CFR, accounting for time delay from diagnosis to death. To this end, we first determined the time distribution from diagnosis to death, allowing variations in the delay over time. We then assessed the age-dependent CFR in Tokyo and Osaka. In Osaka, the risk

SUBMITTER: Hayashi K 

PROVIDER: S-EPMC9744068 | biostudies-literature | 2022 Dec

REPOSITORIES: biostudies-literature