The relationship between temperament, polygenic score for intelligence and cognition: A population-based study of middle-aged adults.

ABSTRACT: We investigated whether temperament modifies an association between polygenic intelligence potential and cognitive test performance in midlife. The participants (n = 1647, born between 1962 and 1977) were derived from the Young Finns Study. Temperament was assessed with Temperament and Character Inventory over a 15-year follow-up (1997, 2001, 2007, 2012). Polygenic intelligence potential was assessed with a polygenic score for intelligence. Cognitive performance (visual memory, reaction time, sustained attention, spatial working memory) was assessed with CANTAB in midlife. The PGSI was significantly associated with the overall cognitive performance and performance in visual memory, sustained attention and working memory tests but not reaction time test. Temperament did not correlate with p

SUBMITTER: Tolli P 

PROVIDER: S-EPMC9744494 | biostudies-literature | 2022 Apr

REPOSITORIES: biostudies-literature