Ontology highlight
ABSTRACT:
SUBMITTER: Kim H
PROVIDER: S-EPMC9745114 | biostudies-literature | 2022
REPOSITORIES: biostudies-literature
Kim Hyejin H Bang Geul G Park Ye Eun YE Park Moonhee M Choi Jung Hoon JH Oh Myung Jin MJ An Hyun Joo HJ Yoo Jong Shin JS Park Youngja Hwang YH Kim Jin Young JY Hwang Heeyoun H
Frontiers in molecular biosciences 20221129
Characterization of therapeutic monoclonal antibodies (mAbs) represents a major challenge for analytical sciences due to their heterogeneity associated with post-translational modifications (PTMs). The protein glycosylation requires comprehensive identification, which could influence on the mAbs' structure and their function. Here, we demonstrated high-resolution tandem mass spectrometry with an ultra-high-performance liquid chromatography for characterization and comparison between biologics an ...[more]