Impact of body composition and genotype on haemodynamics during surgery for pheochromocytoma and paraganglioma.

ABSTRACT:

Background

Maintaining intraoperative haemodynamic stability can reduce cardiovascular complications during surgery for pheochromocytoma and paraganglioma (PPGL). Risk factors such as tumour size and catecholamine levels are reported to predict haemodynamic responses during surgery for PPGL. We hypothesized that additional factors including body composition and genetic information could further improve prediction.

Methods

Consecutive patients with PPGL confirmed by surgical pathology between June 2010 and June 2019 were retrospectively included. Cross-sectional computed tomography images at the L3 level were used to assess body composition parameters including skeletal muscle area and visceral fat area. Next-generation sequencing was performed using a panel containing suscep

SUBMITTER: Pang Y 

PROVIDER: S-EPMC9745493 | biostudies-literature | 2022 Dec

REPOSITORIES: biostudies-literature