Monocyte distribution width as a pragmatic screen for SARS-CoV-2 or influenza infection.

ABSTRACT: Monocyte distribution width (MDW) is a novel marker of monocyte activation, which is known to occur in the immune response to viral pathogens. Our objective was to determine the performance of MDW and other leukocyte parameters as screening tests for SARS-CoV-2 and influenza infection. This was a prospective cohort analysis of adult patients who underwent complete blood count (CBC) and SARS-CoV-2 or influenza testing in an Emergency Department (ED) between January 2020 and July 2021. The primary outcome was SARS-CoV-2 or influenza infection. Secondary outcomes were measures of severity of illness including inpatient hospitalization, critical care admission, hospital lengths of stay and mortality. Descriptive statistics and test performance measures were evaluated for monocyte percentage, M

SUBMITTER: Badaki-Makun O 

PROVIDER: S-EPMC9745720 | biostudies-literature | 2022 Dec

REPOSITORIES: biostudies-literature