Anesthesia and analgesia for common research models of adult mice.

ABSTRACT: Anesthesia and analgesia are major components of many interventional studies on laboratory animals. However, various studies have shown improper reporting or use of anesthetics/analgesics in research proposals and published articles. In many cases, it seems "anesthesia" and "analgesia" are used interchangeably, while they are referring to two different concepts. Not only this is an unethical practice, but also it may be one of the reasons for the proven suboptimal quality of many animal researches. This is a widespread problem among investigations on various species of animals. However, it could be imagined that it may be more prevalent for the most common species of laboratory animals, such as the laboratory mice. In this review, proper anesthetic/analgesic methods for routine procedures

SUBMITTER: Ahmadi-Noorbakhsh S 

PROVIDER: S-EPMC9746144 | biostudies-literature | 2022 Dec

REPOSITORIES: biostudies-literature