Drugs for neglected tropical diseases: availability of age-appropriate oral formulations for young children.

ABSTRACT: It is recognised that paediatric indications and age-appropriate formulations are required to ensure that paediatric populations receive appropriate pharmacotherapeutic treatment. The lack of information on dosing, efficacy and safety data (labelling) is a well-recognised problem for all diseases affecting children. For neglected tropical diseases, the fact that they affect to a large extent poor and marginalised populations in low- and middle-income countries means that there is a low economic return on investment into paediatric development activities compared to other diseases [e.g. human immunodeficiency virus (HIV)]. This review provides an introduction to issues affecting the availability and development of paediatric population-relevant data and appropriate formulations of drugs for

SUBMITTER: Al-Obaidi I 

PROVIDER: S-EPMC9746163 | biostudies-literature | 2022 Dec

REPOSITORIES: biostudies-literature