Association between sex hormone-binding globulin and kidney function in men: results from the SPECT-China study.

ABSTRACT:

Background

The association between sex hormone-binding globulin (SHBG) and renal function has rarely been reported in men. We aimed to investigate the above association in a community-based Chinese population.

Methods

A total of 5027 men were included from the survey on prevalence for metabolic diseases and risk factors, which is a population-based study conducted from 2014 to 2016 in Eastern China. The estimated glomerular filtration rate (eGFR) was calculated according to the chronic kidney disease Epidemiology Collaboration equation. Low eGFR was defined as eGFR <60 mL·min -1 ·1.73 m -2 .

Results

After adjusting for age, smoking, metabolic factors, and testosterone, through increasing quartiles of SHBG, a significantly positive association between SHBG quartiles an

SUBMITTER: Zhang H 

PROVIDER: S-EPMC9746761 | biostudies-literature | 2022 Sep

REPOSITORIES: biostudies-literature