Monitoring real-time transmission heterogeneity from incidence data.

ABSTRACT: The transmission heterogeneity of an epidemic is associated with a complex mixture of host, pathogen and environmental factors. And it may indicate superspreading events to reduce the efficiency of population-level control measures and to sustain the epidemic over a larger scale and a longer duration. Methods have been proposed to identify significant transmission heterogeneity in historic epidemics based on several data sources, such as contact history, viral genomes and spatial information, which may not be available, and more importantly ignore the temporal trend of transmission heterogeneity. Here we attempted to establish a convenient method to estimate real-time heterogeneity over an epidemic. Within the branching process framework, we introduced an instant-individualheterogenous inf

SUBMITTER: Zhang Y 

PROVIDER: S-EPMC9746975 | biostudies-literature | 2022 Dec

REPOSITORIES: biostudies-literature