Association of sepsis-induced cardiomyopathy and mortality: a systematic review and meta-analysis.

ABSTRACT:

Background

The implication of sepsis-induced cardiomyopathy (SIC) to prognosis is controversial, and its association with mortality at different stages remains unclear. We conducted a systematic review and meta-analysis to understand the association between SIC and mortality in septic patients.

Methods

We searched and appraised observational studies regarding the mortality related to SIC among septic patients in PubMed and Embase from inception until 8 July 2021. Outcomes comprised in-hospital and 1-month mortality. We adopted the random-effects model to examine the mortality risk ratio in patients with and without SIC. Meta-regression, subgroup, and sensitivity analyses were applied to examine the outcome's heterogeneity.

Results

Our results, including 20 studies and

SUBMITTER: Lin YM 

PROVIDER: S-EPMC9748009 | biostudies-literature | 2022 Dec

REPOSITORIES: biostudies-literature