Parental pre-pregnancy body mass index and risk of low birth weight in offspring: A prospective cohort study in central China.

ABSTRACT:

Background

Low birth weight (LBW) is one of the most common adverse pregnancy outcomes. Previous studies have consistently shown that maternal body mass index (BMI) status before and during pregnancy is associated with LBW. However, previous studies lacked an association between paternal BMI and the conjunction effect of a couple's BMI and LBW in the offspring. Therefore, we established a cohort of pre-pregnancy couples to prospectively assess the relationship between maternal and paternal pre-pregnancy BMI and offspring LBW, very low birth weight (VLBW), and extremely low birth weight (ELBW).

Methods

A prospective cohort study was established in Central China. A total of 34,104 pregnant women with singleton pregnancies at 8-14 gestational weeks and their husbands were final

SUBMITTER: Wei J 

PROVIDER: S-EPMC9748483 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature