Ontology highlight
ABSTRACT:
SUBMITTER: Hamelmann NM
PROVIDER: S-EPMC9748935 | biostudies-literature | 2022 Dec
REPOSITORIES: biostudies-literature
Hamelmann Naomi M NM Uijttewaal Sjoerd S Hujaya Sry D SD Paulusse Jos M J JMJ
Biomacromolecules 20221116 12
Intracellular delivery of nanoparticles is crucial in nanomedicine to reach optimal delivery of therapeutics and imaging agents. Single-chain polymer nanoparticles (SCNPs) are an interesting class of nanoparticles due to their unique site range of 5-20 nm. The intracellular delivery of SCNPs can be enhanced by using delivery agents. Here, a positive polymer is used to form polyplexes with SCNPs, similar to the strategy of protein and gene delivery. The size and surface charge of the polyplexes w ...[more]