Female factors modulate Sex Peptide's association with sperm in Drosophila melanogaster.

ABSTRACT:

Background

Male-derived seminal fluid proteins (SFPs) that enter female fruitflies during mating induce a myriad of physiological and behavioral changes, optimizing fertility of the mating pair. Some post-mating changes in female Drosophila melanogaster persist for ~10-14 days. Their long-term persistence is because the seminal protein that induces these particular changes, the Sex Peptide (SP), is retained long term in females by binding to sperm, with gradual release of its active domain from sperm. Several other "long-term response SFPs" (LTR-SFPs) "prime" the binding of SP to sperm. Whether female factors play a role in this process is unknown, though it is important to study both sexes for a comprehensive physiological understanding of SFP/sperm interactions and for considerat

SUBMITTER: Misra S 

PROVIDER: S-EPMC9749180 | biostudies-literature | 2022 Dec

REPOSITORIES: biostudies-literature