Antibody responses to second doses of COVID-19 vaccination in lung cancer patients undergoing treatment.

ABSTRACT:

Background

Several reports have revealed that severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection tends to have more severe outcomes in cancer patients. Although vaccination reduces the risk of severe disease, data on antibody titers achieved by vaccination is scarce in cancer patients.

Methods

We collected 79 blood samples (69 lung cancer patients and 10 control individuals) and conducted an anti-SARS-CoV-2 antibody assay to compare the antibody titer achieved with current treatment. Sixty-eight patients (86%) received the BNT162 mRNA vaccine and 11 (14%) received the mRNA-1273 vaccine. They were categorized according to the current treatment: control individuals without cancer (cohort A), lung cancer patients who were treated with cytotoxic chemotherapy

SUBMITTER: Narita D 

PROVIDER: S-EPMC9750888 | biostudies-literature | 2023 Mar

REPOSITORIES: biostudies-literature