A retrospective analysis based on multiple machine learning models to predict lymph node metastasis in early gastric cancer.

ABSTRACT:

Background

Endoscopic submucosal dissection has become the primary option of treatment for early gastric cancer. However, lymph node metastasis may lead to poor prognosis. We analyzed factors related to lymph node metastasis in EGC patients, and we developed a construction prediction model with machine learning using data from a retrospective series.

Methods

Two independent cohorts' series were evaluated including 305 patients with EGC from China as cohort I and 35 patients from Spain as cohort II. Five classifiers obtained from machine learning were selected to establish a robust prediction model for lymph node metastasis in EGC.

Results

The clinical variables such as invasion depth, histologic type, ulceration, tumor location, tumor size, Lauren classification, and

SUBMITTER: Yang T 

PROVIDER: S-EPMC9751349 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature