Association between inflammatory markers and non-alcoholic fatty liver disease in obese children.

ABSTRACT:

Background

Given the high prevalence of non-alcoholic fatty liver disease (NAFLD) in obese children, non-invasive markers of disease to date are still limited and worth exploring.

Objective

This study aimed to evaluate the association between inflammatory markers and NAFLD in obese children.

Methods

We performed a case-control study in Hunan Children's Hospital from September 2020 to September 2021. Study participants were children with obesity diagnosed with NAFLD by abdominal ultrasound examination. Mean platelet volume (MPV), platelet distribution width (PDW), neutrophil, lymphocyte, monocyte, and platelet counts were extracted from medical records and inflammatory cytokines were measured by enzyme-linked immunosorbent assay (ELISA). Multivariable logistic regressi

SUBMITTER: Duan Y 

PROVIDER: S-EPMC9751435 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature