Online Hemodiafiltration Compared to Conventional Hemodialysis in Critically Ill Patients.

ABSTRACT:

Introduction

Online hemodiafiltration (HDF) has been increasingly used for improved clearance of middle molecular weight toxins. The impact of this mode of clearance is unknown in critically ill patients. We aimed to determine whether the use of HDF in acute kidney injury (AKI) is associated with lower mortality and improved kidney recovery up to 90 days after initiation of therapy.

Methods

Single-center retrospective cohort study using data from 2017 to 2020 of adults with AKI who initiated intermittent renal replacement therapy (IRRT) in the intensive care unit (ICU), using either hemodialysis (HD) or HDF depending on the maintenance status of the water system without regards for patient characteristics. We assessed association with patient-events and session-events using

SUBMITTER: Piotte J 

PROVIDER: S-EPMC9751768 | biostudies-literature | 2022 Nov

REPOSITORIES: biostudies-literature