A prognostic nomogram for papillary thyroid cancer lymph node metastasis based on immune score.

ABSTRACT:

Background

Papillary thyroid cancer (PTC) is the most common subtype of thyroid cancer and is characterized by an overall good prognosis and early-stage lymph node metastasis. The immune microenvironment is believed to play a crucial role in PTC initiation, progression and metastasis. However, to our knowledge, prognostic tools for thyroid cancer metastasis based on immune scores have not been adequately explored. This study aimed to construct a clinical nomogram to predict lymph node metastasis in patients with PTC.

Methods

The genomic data and clinical-pathological characteristics of 447 PTC subjects were obtained from TCGA (The Cancer Genome Atlas data). Logistic regression models were performed for univariate and multivariate analyses to identify significant prediction f

SUBMITTER: Lu Y 

PROVIDER: S-EPMC9751967 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature