CNS inflammatory demyelinating events after COVID-19 vaccines: A case series and systematic review.

ABSTRACT:

Background

Vaccinations provided the most effective tool to fight the SARS-CoV-2 pandemic. It is now well established that COVID-19 vaccines are safe for the general population; however, some cases of rare adverse events following immunization have been described, including CNS Inflammatory Demyelinating Events (CIDEs). Although observational studies are showing that these events are rare and vaccines' benefits highly outweigh the risks, collecting and characterizing post-COVID-19 vaccine CIDEs might be relevant to single out potential risk factors and suggest possible underlying mechanisms.

Methods

Here we describe six CIDEs, including two acute transverse myelitis (ATM), three multiple sclerosis (MS), and one neuromyelitis optica spectrum disorder (NMOSD), occurring betwee

SUBMITTER: Rinaldi V 

PROVIDER: S-EPMC9752005 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature