Predicting the grade of meningiomas by clinical-radiological features: A comparison of precontrast and postcontrast MRI.

ABSTRACT:

Objectives

Postcontrast magnetic resonance imaging (MRI) is important for the differentiation between low-grade (WHO I) and high-grade (WHO II/III) meningiomas. However, nephrogenic systemic fibrosis and cerebral gadolinium deposition are major concerns for postcontrast MRI. This study aimed to develop and validate an accessible risk-scoring model for this differential diagnosis using the clinical characteristics and radiological features of precontrast MRI.

Methods

From January 2019 to October 2021, a total of 231 meningioma patients (development cohort n = 137, low grade/high grade, 85/52; external validation cohort n = 94, low-grade/high-grade, 60/34) were retrospectively included. Fourteen types of demographic and radiological characteristics were evaluated by logistic r

SUBMITTER: Yao Y 

PROVIDER: S-EPMC9752076 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature