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Mycetoma caused by Madurella mycetomatis in immunocompromised patients - a case report and systematic literature review.


ABSTRACT: The aim of this study was to review the available literature concerning Madura foot ("mycetoma") caused by Madurella mycetomatis in immunocompromised patients. With a systematic literature search, we identified only three papers, describing a total of three immunocompromised patients. Hence, the clinical presentation and prognosis of the disease in this patient population have not yet been well described. In addition, we present a case from our institution, illustrating the complexity of the treatment of this rare disease. Although very rare in non-endemic countries, we emphasize that mycetoma should be included in the differential diagnoses of (immunocompromised) patients who have been residing in a geographical area where the disease is endemic and presenting with soft tissue inflammation of one of the extremities.

SUBMITTER: Hoogervorst LA 

PROVIDER: S-EPMC9752710 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature

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Mycetoma caused by <i>Madurella mycetomatis</i> in immunocompromised patients - a case report and systematic literature review.

Hoogervorst Lotje A LA   Op de Coul Lindsey S LS   Ray Arghya A   de Witte Pieter Bas PB   de Boer Mark G J MGJ  

Journal of bone and joint infection 20221121 6


The aim of this study was to review the available literature concerning Madura foot ("mycetoma") caused by <i>Madurella mycetomatis</i> in immunocompromised patients. With a systematic literature search, we identified only three papers, describing a total of three immunocompromised patients. Hence, the clinical presentation and prognosis of the disease in this patient population have not yet been well described. In addition, we present a case from our institution, illustrating the complexity of  ...[more]

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