Magnetic resonance imaging negative myelopathy in Leber's hereditary optic neuropathy: a case report.

ABSTRACT:

Background

Leber's hereditary optic neuropathy (LHON) is a common form of mitochondrial disease. The typical clinical presentation of LHON is subacute, painless loss of vision resulting from bilateral optic nerve atrophy. Moreover, extra-ocular manifestations such as cardiac conduction abnormalities and neurological manifestations such as multiple sclerosis (MS) like disease or parkinsonism are encountered in some patients. Abnormal findings in spinal cord MR imaging or in the cerebrospinal fluid (CSF) have been observed in previous cases of LHON-associated myelopathy.

Case presentation

We report a male patient with LHON who developed symptoms of myelopathy including gait unsteadiness, enhanced deep tendon reflexes and sensory loss of the lower extremities. Imaging of the br

SUBMITTER: Martikainen MH 

PROVIDER: S-EPMC9753244 | biostudies-literature | 2022 Dec

REPOSITORIES: biostudies-literature