Assessing the health risk of living near composting facilities on lung health, fungal and bacterial disease in cystic fibrosis: a UK CF Registry study.

ABSTRACT:

Aim

To explore the health risk of living near permitted composting sites (PCSs) on disease severity in children and adults with cystic fibrosis (CF) across the UK.  METHODS: A semi-individual cross-sectional study was used to examine the risk of disease severity in people with CF (pwCF) within and beyond 4 km of PCSs in the UK in 2016. All pwCF registered in the UK CF Registry were eligible for this study. Linear and Poisson regressions, adjusted for age, gender, genotype, BMI, Pseudomonas aeruginosa and deprivation, were used to quantify associations between distance to a PCS and percent predicted forced expiratory volume in one second (ppFEV₁), pulmonary exacerbations (#IVdays), and fungal and bacterial infections.

Results

The mean age of the 9,361 pwCF (3,931 c

SUBMITTER: Khan MS 

PROVIDER: S-EPMC9753251 | biostudies-literature | 2022 Dec

REPOSITORIES: biostudies-literature