Ontology highlight
ABSTRACT:
SUBMITTER: Petriman NA
PROVIDER: S-EPMC9753473 | biostudies-literature | 2022 Dec
REPOSITORIES: biostudies-literature
Petriman Narcis A NA Loureiro-López Marta M Taschner Michael M Zacharia Nevin K NK Georgieva Magdalena M MM Boegholm Niels N Wang Jiaolong J Mourão André A Russell Robert B RB Russell Robert B RB Andersen Jens S JS Lorentzen Esben E
The EMBO journal 20221110 24
Cilia are ubiquitous eukaryotic organelles impotant for cellular motility, signaling, and sensory reception. Cilium formation requires intraflagellar transport of structural and signaling components and involves 22 different proteins organized into intraflagellar transport (IFT) complexes IFT-A and IFT-B that are transported by molecular motors. The IFT-B complex constitutes the backbone of polymeric IFT trains carrying cargo between the cilium and the cell body. Currently, high-resolution struc ...[more]