Endophytic bacteria of Fagonia indica Burm. f revealed to harbour rich secondary antibacterial metabolites.

ABSTRACT: Endophytic bacteria are the source of novel bioactive compounds, used as therapeutic agent. Molecular docking is a computational technique use frequently, to find novel drugs targets and drugs-receptors interactions. The current study was designed to isolate and identify endophytic bacteria for the extraction of bioactive compounds. Further, to characterized extracts and to explore compounds interactions with bacterial cell wall and outer membrane synthesizing proteins. Endophytes were identified using 16s rRNA amplification technique. For bioactive compounds, solvent extraction method was followed and characterized further through GC-MS analysis. To find targets and drugs-receptors interactions, molecular docking studies and biological assays were performed. The isolated endophytes belong

SUBMITTER: Rahman L 

PROVIDER: S-EPMC9754247 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature