Dataset Information
Late (≥ 7 days) inhaled corticosteroids to reduce bronchopulmonary dysplasia in preterm infants.
Ontology highlight
ABSTRACT:
SUBMITTER: Onland W
PROVIDER: S-EPMC9754672 | biostudies-literature | 2022 Dec
REPOSITORIES: biostudies-literature
Publications
Late (≥ 7 days) inhaled corticosteroids to reduce bronchopulmonary dysplasia in preterm infants.
The Cochrane database of systematic reviews 20221215
<h4>Background</h4>Bronchopulmonary dysplasia (BPD), defined as oxygen dependence at 36 weeks' postmenstrual age (PMA), remains an important complication of prematurity. Pulmonary inflammation plays a central role in the pathogenesis of BPD. Attenuating pulmonary inflammation with postnatal systemic corticosteroids reduces the incidence of BPD in preterm infants but may be associated with an increased risk of adverse neurodevelopmental outcomes. Local administration of corticosteroids via inhala ...[more]
