Graft Detachment after Descemet Membrane Endothelial Keratoplasty with and without Cataract Surgery.

ABSTRACT:

Purpose

To evaluate graft detachment after Descemet membrane endothelial keratoplasty (DMEK) in pseudophakic eyes and DMEK combined with cataract surgery (triple DMEK).

Design

Analysis of 3 single-center prospective cohort studies and 1 randomized controlled trial.

Participants

Participants with Fuchs' endothelial corneal dystrophy.

Methods

A validated neural network for image segmentation quantified graft detachment on anterior segment OCT (AS-OCT) images 3 days after DMEK and at the 2-week postoperative visit. Area and volume of graft detachment were compared between DMEK only and triple DMEK using generalized estimating equation models and adjusting for participant age and the size of the air bubble.

Main outcome measures

Area and volume of DMEK graft

SUBMITTER: Kladny AS 

PROVIDER: S-EPMC9754956 | biostudies-literature | 2022 Dec

REPOSITORIES: biostudies-literature