Preoperative pelvic MRI and 2-[¹⁸F]FDG PET/CT for lymph node staging and prognostication in endometrial cancer-time to revisit current imaging guidelines?

ABSTRACT:

Objective

This study presents the diagnostic performance of four different preoperative imaging workups (IWs) for prediction of lymph node metastases (LNMs) in endometrial cancer (EC): pelvic MRI alone (IW1), MRI and [¹⁸F]FDG-PET/CT in all patients (IW2), MRI with selective [¹⁸F]FDG-PET/CT if high-risk preoperative histology (IW3), and MRI with selective [¹⁸F]FDG-PET/CT if MRI indicates FIGO stage ≥ 1B (IW4).

Methods

In 361 EC patients, preoperative staging parameters from both pelvic MRI and [¹⁸F]FDG-PET/CT were recorded. Area under receiver operating characteristic curves (ROC AUC) compared the diagnostic performance for the different imaging parameters and workups for predicting surgicopathological FIGO stage. Survival data were

SUBMITTER: Fasmer KE 

PROVIDER: S-EPMC9755079 | biostudies-literature | 2023 Jan

REPOSITORIES: biostudies-literature