Impact of diet on human nutrition, immune response, gut microbiome, and cognition in an isolated and confined mission environment.

ABSTRACT: Long-duration spaceflight impacts human physiology, including well documented immune system dysregulation. The space food system has the potential to serve as a countermeasure to maladaptive physiological changes during spaceflight. However, the relationship between dietary requirements, the food system, and spaceflight adaptation requires further investigation to adequately define countermeasures and prioritize resources on future spaceflight missions. We evaluated the impact of an enhanced spaceflight diet, with increased quantity and variety of fruits, vegetables, fish, and other foods rich in flavonoids and omega-3 fatty acids, compared to a standard spaceflight diet on multiple health and performance outcomes in 16 subjects over four 45-day closed chamber missions in the NASA Human Ex

SUBMITTER: Douglas GL 

PROVIDER: S-EPMC9755260 | biostudies-literature | 2022 Dec

REPOSITORIES: biostudies-literature