The association between albumin levels and survival in patients treated with immune checkpoint inhibitors: A systematic review and meta-analysis.

ABSTRACT: Background: The albumin levels may potentially be used as a prognostic biomarker in patients with cancertreated with immune checkpoint inhibitors (ICIs) due to its close relationship with nutritional and inflammatory status. However, the available data is limited with heterogeneous patient cohorts, sample sizes and variable cut-offs. Therefore, we conducted a systematic review and meta-analysis to evaluate the association between survival outcomes and albumin levels in patients treated with ICIs. Methods: We conducted a systematic review using the PubMed, Web of Science, and Embase databases to filter the published studies up to 1 June 2022. The meta-analyses were performed with the generic inverse-variance method with a random-effects model due to the high degree of heteroge

SUBMITTER: Guven DC 

PROVIDER: S-EPMC9756377 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature