Guts within guts: the microbiome of the intestinal helminth parasite Ascaris suum is derived but distinct from its host.

ABSTRACT:

Background

Intestinal helminths are extremely prevalent among humans and animals. In particular, intestinal roundworms affect more than 1 billion people around the globe and are a major issue in animal husbandry. These pathogens live in intimate contact with the host gut microbiota and harbor bacteria within their own intestines. Knowledge of the bacterial host microbiome at the site of infection is limited, and data on the parasite microbiome is, to the best of our knowledge, non-existent.

Results

The intestinal microbiome of the natural parasite and zoonotic macropathogen, Ascaris suum was analyzed in contrast to the diversity and composition of the infected host gut. 16S sequencing of the parasite intestine and host intestinal compartments showed that the parasite gut has

SUBMITTER: Midha A 

PROVIDER: S-EPMC9756626 | biostudies-literature | 2022 Dec

REPOSITORIES: biostudies-literature