Quality of life outcomes in incidental and operated meningiomas (QUALMS): a cross-sectional cohort study.

ABSTRACT:

Introduction

Few studies have evaluated meningioma patients' longer-term health-related quality of life (HRQoL) following diagnosis and treatment, particularly in those with incidental, actively monitored tumours.

Methods

A single-center, cross-sectional study was completed. Adult patients with surgically managed or actively monitored meningioma with more than five years of follow-up were included. The patient-reported outcome measures RAND SF-36, EORTC QLQ-C30 and QLQ-BN20 were used to evaluate HRQoL. HRQoL scores were compared to normative population data. Outcome determinants were evaluated using multivariate linear regression analysis.

Results

243 patient responses were analyzed, and the mean time from diagnosis was 9.8 years (range 5.0-40.3 years). Clinically rel

SUBMITTER: Keshwara SM 

PROVIDER: S-EPMC9756745 | biostudies-literature | 2023 Jan

REPOSITORIES: biostudies-literature