Hygiene of housing conditions and proinflammatory signals alter gene expressions in porcine adipose tissues and blood cells.

ABSTRACT: Adipose tissue is an organ with metabolic, endocrine and immune functions. In this tissue, the expressions of genes associated with several metabolic pathways, including lipid metabolism, have been shown to be affected by genetic selection for feed efficiency, an important trait to consider in livestock. We hypothesized that the stimulation of immune system caused by poor hygiene conditions of housing impacts the molecular and cellular features of adipose tissue and that the impact may differ between pigs that diverge in feed efficiency. At the age of 12 weeks, Large White pigs from two genetic lines divergent for residual feed intake (RFI) were housed in two contrasting hygiene conditions (good vs poor). After six weeks of exposure, pigs were slaughtered (n = 36). Samples of blood,

SUBMITTER: Quemener A 

PROVIDER: S-EPMC9756862 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature