Neurocognition in adults with intracranial tumors: does location really matter?

ABSTRACT:

Objective

As preservation of cognitive functioning increasingly becomes important in the light of ameliorated survival after intracranial tumor treatments, identification of eloquent brain areas would enable optimization of these treatments.

Methods

This cohort study enrolled adult intracranial tumor patients who received neuropsychological assessments pre-irradiation, estimating processing speed, verbal fluency and memory. Anatomical magnetic resonance imaging scans were used for multivariate voxel-wise lesion-symptom predictions of the test scores (corrected for age, gender, educational level, histological subtype, surgery, and tumor volume). Potential effects of histological and molecular subtype and corresponding WHO grades on the risk of cognitive impairment were invest

SUBMITTER: Sleurs C 

PROVIDER: S-EPMC9758085 | biostudies-literature | 2022 Dec

REPOSITORIES: biostudies-literature