Association of extent of resection and functional outcomes in diffuse low-grade glioma: systematic review & meta-analysis.

ABSTRACT:

Background

Surgical resection offers survival benefits in patients with diffuse low-grade glioma (DLGG) but its association with functional outcomes is uncertain. This systematic review assessed functional outcomes associated with extent of resection (EoR) in adults with DLGG.

Methods

We searched Medline, Embase and CENTRAL on the 19th of February 2021 for observational studies reporting functional outcomes after surgical resection for patients aged ≥ 18 years with a new diagnosis of supratentorial DLGG according to any World Health Organization classification of primary brain tumors. The Newcastle-Ottawa Scale (NOS) informed our risk of bias assessments. The proportion of patients returning to work within 12 months entered a random-effects meta-analysis. PROSPERO registrati

SUBMITTER: Elsheikh M 

PROVIDER: S-EPMC9758089 | biostudies-literature | 2022 Dec

REPOSITORIES: biostudies-literature