A simple high-throughput method for automated detection of Drosophila melanogaster light-dependent behaviours.

ABSTRACT:

Background

Like most living organisms, the fruit fly Drosophila melanogaster exhibits strong and diverse behavioural reactions to light. Drosophila is a diurnal animal that displays both short- and long-term responses to light, important for, instance, in avoidance and light wavelength preference, regulation of eclosion, courtship, and activity, and provides an important model organism for understanding the regulation of circadian rhythms both at molecular and circuit levels. However, the assessment and comparison of light-based behaviours is still a challenge, mainly due to the lack of a standardised platform to measure behaviour and different protocols created across studies. Here, we describe the Drosophila Interactive System for Controlled Optical manipulations (DISCO), a low-c

SUBMITTER: Moulin TC 

PROVIDER: S-EPMC9758938 | biostudies-literature | 2022 Dec

REPOSITORIES: biostudies-literature