Higher scores on autonomic symptom scales in pediatric patients with neurodevelopmental disorders of known genetic etiology.

ABSTRACT:

Introduction

Features of underlying autonomic dysfunction, including sleep disturbances, gastrointestinal problems, and atypical heart rate, have been reported in neurodevelopmental conditions, including autism spectrum disorder (ASD). The current cross-sectional, between-groups study aimed to quantify symptoms of autonomic dysfunction in a neurodevelopmental pediatric cohort characterized by clinical diagnoses as well as genetic etiology.

Method

The Pediatric Autonomic Symptom Scales (PASS) questionnaire was used to assess autonomic features across a group of patients with clinical neurodevelopmental diagnoses (NPD; N = 90) and genetic etiologies. Patients were subdivided based on either having a clinical ASD diagnosis (NPD-ASD; n = 37) or other non-ASD neurodevelopmental d

SUBMITTER: DiCriscio AS 

PROVIDER: S-EPMC9759134 | biostudies-literature | 2022 Dec

REPOSITORIES: biostudies-literature