Gastrointestinal Microbiota and Breast Cancer Chemotherapy Interactions: A Systematic Review.

ABSTRACT: Breast cancer is the most common type of cancer in women besides basal cell and squamous cell skin cancer. The current systemic therapy guidelines for this heterogeneous disease are mainly based on the molecular subtypes. However, more research is required to improve rates of therapy resistance and prevent side effects. Previous studies have shown that the human gut microbiota may have an important role in carcinogenesis as well as therapy outcomes, but this factor has not yet been integrated into therapy protocols. This systematic review aims to analyze how response rates and side effect profiles of breast cancer systemic therapies may be affected by the gastrointestinal microbiota. A literature search was performed using multiple databases and keywords related to gastrointestinal microbi

SUBMITTER: Csendes D 

PROVIDER: S-EPMC9760128 | biostudies-literature | 2022 Nov

REPOSITORIES: biostudies-literature