Effect of Caffeine on Colonic Manometry in Children.

ABSTRACT:

Objectives

Coffee and caffeinated products have been widely consumed for many centuries. Previous adult studies have suggested that both coffee and decaffeinated beverages induce colonic motility. However, no study has been conducted in pediatrics, and the role of caffeine alone in pediatric colonic motility needs to be explored.

Methods

A prospective study of pediatric patients undergoing standard colonic motility testing that were able to consume caffeinated coffee, decaffeinated coffee, and caffeine tablet during colonic manometry. Patients who had a gastrocolonic reflex and high amplitude propagated contractions (HAPCs) in response to intraluminal administration of bisacodyl in the colon were included in the final analyses.

Results

Thirty-eight patients were recru

SUBMITTER: Mehta V 

PROVIDER: S-EPMC9760462 | biostudies-literature | 2023 Jan

REPOSITORIES: biostudies-literature